Cristina-Maria Sirrenberg-Cruciat

Faculty Natural Sciences

Prof. Dr. rer. nat. Cristina-Maria Sirrenberg-Cruciat

Address :

Esslingen City Centre Campus
Room: S 04.109
Kanalstraße 33
73728 Esslingen


Head of - Biochemistry laboratory

Academic Director - Biotechnology (B.Sc.)

consultation hours

Nach Vereinbarung


Curriculum Vitae





Since 2015

Professor of Biochemistry and Process Chromatography,

University of Applied Sciences, Esslingen



2003 - 2015

Senior Scientist with Christof Niehrs,

German Cancer Research Center, Heidelberg


2000 - 2003

Scientist, Cellzome AG, Heidelberg



1997 - 2000

PhD, Lab of Walter Neupert, Ludwig Maximilians University, Munich


Ausgewählte Publikationen


1. Cruciat, C.M. (2014). Casein kinase 1 and Wnt/b-catenin signaling. Curr. Opin. Cell Biol., 31, 46-55.


2. Cruciat, C.M., Dolde, C., De Groot, R., Ohkawara, B., Reinhard, C., Korswagen, H.C., and Niehrs, C. (2013). RNA Helicase DDX3 is a regulatory subunit of Casein Kinase 1 in Wnt/b-catenin signaling. Science, 339, 1436-1441.


3. Glinka, A., Dolde, C., Kirsch, N., Huang, Y.L., Kazanskaya, O., Ingelfinger, D., Boutros, M., Cruciat,C.M.*, and Niehrs, C*. (2011). LGR4 and LGR5 are R-spondin receptors mediating Wnt/b-catenin and Wnt/PCP signaling. EMBO reports, 12, 1055-1061.

*joint corresponding authorship


4. Cruciat C.M., Ohkawara, B., Acebron, S.P., Karaulanov, E., Reinhard, C., Ingelfinger, D., Boutros, M., Niehrs, C. (2010). Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science, 327, 459-463.


Apply for summer semester 2021!

Application period for programmes starting in the summer semester 2021
Bachelor’s programmes: 1 December 2020 to 15 january 2021
Master’s programmes (German): 15 October 2020 to 15 January 2021
Applicants to our international programmes should please see the Graduate School website for deadlines

Apply now