Foto Cristina-Maria Sirrenberg-Cruciat

Science, Energy and Building Services Prof. Dr. rer. nat. Cristina-Maria Sirrenberg-Cruciat


Esslingen City Centre Campus
Room: S 04.109
Kanalstraße 33
73728 Esslingen

+49 711 397-3114


Beauftragte für die Biologische Sicherheit

Head of Biochemistry laboratory

Academic Director Biotechnology

consultation hours

Nach Vereinbarung


Curriculum Vitae





Since 2015

Professor of Biochemistry and Process Chromatography,

University of Applied Sciences, Esslingen



2003 - 2015

Senior Scientist with Christof Niehrs,

German Cancer Research Center, Heidelberg


2000 - 2003

Scientist, Cellzome AG, Heidelberg



1997 - 2000

PhD, Lab of Walter Neupert, Ludwig Maximilians University, Munich


Ausgewählte Publikationen

1. Cruciat, C.M. (2014). Casein kinase 1 and Wnt/b-catenin signaling. Curr. Opin. Cell Biol., 31, 46-55.

2. Cruciat, C.M., Dolde, C., De Groot, R., Ohkawara, B., Reinhard, C., Korswagen, H.C., and Niehrs, C. (2013). RNA Helicase DDX3 is a regulatory subunit of Casein Kinase 1 in Wnt/b-catenin signaling. Science, 339, 1436-1441.


3. Glinka, A., Dolde, C., Kirsch, N., Huang, Y.L., Kazanskaya, O., Ingelfinger, D., Boutros, M., Cruciat,C.M.*, and Niehrs, C*. (2011). LGR4 and LGR5 are R-spondin receptors mediating Wnt/b-catenin and Wnt/PCP signaling. EMBO reports, 12, 1055-1061.

*joint corresponding authorship


4. Cruciat C.M., Ohkawara, B., Acebron, S.P., Karaulanov, E., Reinhard, C., Ingelfinger, D., Boutros, M., Niehrs, C. (2010). Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science, 327, 459-463.



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