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Cristina-Maria Sirrenberg-Cruciat

Faculty Science, Energy and Building Services

Prof. Dr. rer. nat. Cristina-Maria Sirrenberg-Cruciat

Address :

Esslingen City Centre Campus
Room: S 04.109
Kanalstraße 33
73728 Esslingen

consultation hours

Nach Vereinbarung


Curriculum Vitae





Since 2015

Professor of Biochemistry and Process Chromatography,

University of Applied Sciences, Esslingen



2003 - 2015

Senior Scientist with Christof Niehrs,

German Cancer Research Center, Heidelberg


2000 - 2003

Scientist, Cellzome AG, Heidelberg



1997 - 2000

PhD, Lab of Walter Neupert, Ludwig Maximilians University, Munich


Ausgewählte Publikationen


1. Cruciat, C.M. (2014). Casein kinase 1 and Wnt/b-catenin signaling. Curr. Opin. Cell Biol., 31, 46-55.


2. Cruciat, C.M., Dolde, C., De Groot, R., Ohkawara, B., Reinhard, C., Korswagen, H.C., and Niehrs, C. (2013). RNA Helicase DDX3 is a regulatory subunit of Casein Kinase 1 in Wnt/b-catenin signaling. Science, 339, 1436-1441.


3. Glinka, A., Dolde, C., Kirsch, N., Huang, Y.L., Kazanskaya, O., Ingelfinger, D., Boutros, M., Cruciat,C.M.*, and Niehrs, C*. (2011). LGR4 and LGR5 are R-spondin receptors mediating Wnt/b-catenin and Wnt/PCP signaling. EMBO reports, 12, 1055-1061.

*joint corresponding authorship


4. Cruciat C.M., Ohkawara, B., Acebron, S.P., Karaulanov, E., Reinhard, C., Ingelfinger, D., Boutros, M., Niehrs, C. (2010). Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science, 327, 459-463.


Apply for winter semester 2021/22!

The application period for our bachelor's degree programmes runs to 31 July 2021.
For the master's programmes, the application deadline is 15 July. Please note the different application times for our international master's programmes.

Apply now